Exsil Avanti BDS C18 is a high-efficiency octadecyl bonded silica stationary phase built on the advanced Avanti BDS silica platform. Developed for demanding reversed-phase HPLC and UHPLC applications, this phase delivers strong hydrophobic retention while significantly reducing residual silanol activity to ensure excellent peak symmetry and reproducibility.
The base-deactivation technology minimizes secondary interactions between silica surface silanols and basic analytes, effectively reducing peak tailing — especially for amines, alkaloids, and nitrogen-containing pharmaceuticals. This results in sharper peaks, improved quantification accuracy, and more predictable retention behavior, making Exsil Avanti BDS C18 a reliable choice for pharmaceutical, environmental, and analytical laboratories. The long-chain C18 functionality provides powerful hydrophobic selectivity, enabling high-resolution separations of non-polar and moderately polar compounds. Combined with the highly purified spherical silica matrix, the phase offers excellent mechanical stability, consistent packing performance, and long column lifetime — even under high-pressure UHPLC conditions.
Exsil Avanti BDS C18 combines powerful C18 hydrophobic selectivity with advanced base-deactivation technology—delivering reliable, high-resolution, and reproducible reversed-phase separations for modern analytical laboratories.
Base-deactivated (BDS) C18 bonded silica phase
Strong hydrophobic retention with minimized silanol interactions
Improved peak symmetry for basic compounds
High efficiency and reproducible chromatographic results
Robust spherical silica for UHPLC compatibility
Suitable for gradient and isocratic reversed-phase separations
Pharmaceutical API analysis and impurity profiling
Stability studies and degradation product analysis
Separation of basic and hydrophobic compounds
Environmental and food safety testing
Routine quality control and method development
| Particle Sizes |
|
|---|---|
| Pore Size | 145 Å |
| Surface Area | 185 m²/g |
| Phase/Modification | C18 |
| Particle Type | |
| Separation Mode | |
| USP Code | |
| Endcapping | Yes |
| Carbonload | 11 % |
| pH Range | 2 - 8 |
| Phase | Material Number |
|---|---|
| Exsil Avanti BDS C18, 1.5 µm | 6136923. |
| Exsil Avanti BDS C18, 3 µm | 5136639. |
| Exsil Avanti BDS C18, 5 µm | 5136649. |
| Exsil Avanti BDS C18, 10 µm | 5136758. |