Exsil Avanti BDS C8 is a high-performance octyl bonded silica stationary phase built on the advanced Avanti BDS silica platform. Designed for modern reversed-phase HPLC and UHPLC applications, this phase combines moderate hydrophobic retention with significantly reduced silanol activity to ensure superior chromatographic performance — especially for basic and polar analytes.
The base-deactivated surface minimizes unwanted secondary interactions between residual silanol groups and amine-containing compounds. As a result, peak tailing is reduced, peak symmetry is improved, and retention behavior becomes more reproducible, making Exsil Avanti BDS C8 particularly suitable for pharmaceutical analysis and impurity profiling. With its balanced C8 hydrophobic selectivity, the phase offers shorter retention times compared to C18 materials while maintaining excellent resolution. The highly purified spherical silica matrix ensures mechanical robustness, consistent packing quality, and reliable performance under high-pressure UHPLC conditions.
Exsil Avanti BDS C8 is fully compatible with aqueous-organic gradient systems and commonly used mobile phase modifiers. Its optimized surface chemistry provides a stable chromatographic platform for demanding analytical workflows.
Base-deactivated C8 bonded phase
Reduced silanol activity for improved peak symmetry
Moderate hydrophobic retention with controlled selectivity
High efficiency and reproducible retention behavior
Robust spherical silica for long column lifetime
Suitable for HPLC and UHPLC applications
Analysis of basic pharmaceuticals and APIs
Impurity profiling and stability testing
Separation of moderately hydrophobic compounds
Environmental and food safety analysis
Routine quality control and method development
| Particle Sizes |
|
|---|---|
| Pore Size | 145 Å |
| Surface Area | 185 m²/g |
| Phase/Modification | C8 |
| Particle Type | |
| Separation Mode | |
| USP Code | |
| Endcapping | Yes |
| Carbonload | 6 % |
| pH Range | 2 - 8 |
| Phase | Material Number |
|---|---|
| Exsil Avanti BDS C8, 3 µm | 5136640. |
| Exsil Avanti BDS C8, 5 µm | 5136641. |
| Exsil Avanti BDS C8, 10 µm | 6136883. |