Exsil Avanti BDS Fluoro

Fluorinated Phase for Alternative Selectivity in Reversed-Phase HPLC

Exsil Avanti BDS Fluoro is a high-performance fluorinated reversed-phase silica based on the advanced Avanti BDS platform. The phase is bonded with a highly stable tridecafluorooctyl ligand and carefully endcapped, delivering unique selectivity characteristics beyond conventional alkyl phases.

Fluorinated stationary phases offer distinctive chromatographic behavior. In addition to hydrophobic retention similar to C8 or C18 phases, they exhibit oleophobic character and enhanced interactions with fluorinated analytes. While these selectivity differences may be subtle, they can provide valuable resolution advantages for structurally related compounds and fluorine-containing species. The base-deactivated silica backbone significantly reduces residual silanol activity, resulting in excellent peak shape for basic compounds under low pH conditions. Compared to a standard C8 phase, Exsil Avanti BDS Fluoro typically provides longer retention with alternative selectivity, making it a powerful tool for method optimization and impurity profiling.

Exsil Avanti BDS Fluoro combines stable fluorinated ligand chemistry with advanced base-deactivated silica — delivering distinctive selectivity, improved peak symmetry, and reliable reversed-phase performance for challenging analytical separations.