Exsil Avanti C8 (2) is a premium octyl bonded silica stationary phase featuring advanced endcapping technology, designed for high-performance reversed-phase HPLC and UHPLC separations. The endcapped surface minimizes residual silanol activity, reducing secondary interactions and improving peak symmetry — especially for basic and polar analytes.
The balanced hydrophobic retention of the C8 phase offers optimal selectivity between shorter C4/C6 phases and longer C18 materials, enabling efficient separations with moderate retention times. The enhanced surface deactivation provided by endcapping results in improved reproducibility, reduced tailing, and superior chromatographic robustness, making Exsil Avanti C8 (2) ideal for demanding analytical workflows. Built on the advanced Exsil Avanti high-purity spherical silica platform, this phase delivers excellent mechanical strength, uniform packing performance, and long column lifetime — even under high-pressure UHPLC conditions. It is fully compatible with aqueous/organic gradient systems and common modifiers such as TFA and formic acid.
Exsil Avanti C8 (2) combines balanced C8 hydrophobic selectivity with optimized surface deactivation — delivering precise, reproducible, and high-resolution reversed-phase separations for modern HPLC and UHPLC laboratories.
Octyl bonded phase with advanced endcapping
Reduced silanol activity for improved peak symmetry
Moderate hydrophobic retention with balanced selectivity
High efficiency and reproducible chromatographic performance
Robust spherical silica for analytical and preparative use
Compatible with gradient and isocratic RP-HPLC methods
Reversed-phase separation of pharmaceuticals and APIs
Analysis of basic and moderately polar compounds
Impurity profiling and stability studies
Environmental and food analysis
Routine quality control and method development
| Particle Sizes |
|
|---|---|
| Pore Size | 130 Å |
| Surface Area | 195 m²/g |
| Phase/Modification | C8 |
| Particle Type | |
| Separation Mode | |
| USP Code | |
| Endcapping | Yes |
| Carbonload | 6 % |
| pH Range | 2 - 8 |
| Phase | Material Number |
|---|---|
| Exsil Avanti C8 (2), 1.5 µm | 5136624. |
| Exsil Avanti C8 (2), 3 µm | 5136626. |
| Exsil Avanti C8 (2), 5 µm | 5136627. |