Exsil Avanti ODS is a premium C18 bonded silica stationary phase engineered for high-resolution reversed-phase HPLC and UHPLC separations. Designed for modern analytical workflows, this phase delivers strong hydrophobic retention, excellent peak symmetry, and outstanding reproducibility across a broad range of analytes.
The long-chain C18 surface provides enhanced retention for non-polar and moderately polar compounds, making Exsil Avanti ODS the preferred choice for pharmaceutical analysis, impurity profiling, stability testing, and environmental applications. Its optimized surface chemistry minimizes unwanted secondary interactions, ensuring sharp, symmetrical peaks — even for basic or structurally complex molecules. Built on the advanced Exsil Avanti high-purity spherical silica platform, this stationary phase offers uniform particle morphology, superior mechanical stability, and consistent packing performance. The result is high chromatographic efficiency and reliable operation under high-pressure UHPLC conditions. Exsil Avanti ODS is fully compatible with aqueous-organic gradient systems and commonly used mobile phase modifiers such as formic acid or TFA.
Exsil Avanti ODS combines powerful C18 hydrophobic selectivity with high-efficiency silica technology — delivering reliable, high-resolution separations for demanding analytical and regulatory applications.
C18 (ODS) bonded silica phase for reversed-phase HPLC/UHPLC
Strong hydrophobic retention and balanced selectivity
High efficiency with excellent peak symmetry
Robust spherical silica for long column lifetime
Optimized surface chemistry for reproducible results
Compatible with gradient and isocratic RP methods
Pharmaceutical analysis and API quantification
Impurity profiling and stability studies
Environmental and food safety testing
Method development in reversed-phase chromatography
Routine quality control and high-throughput analysis
| Particle Sizes |
|
|---|---|
| Pore Size | 130 Å |
| Surface Area | 195 m²/g |
| Phase/Modification | C18 |
| Particle Type | |
| Separation Mode | |
| USP Code | |
| Endcapping | Yes |
| Carbonload | 12.5 % |
| pH Range | 2 - 8 |
| Phase | Material Number |
|---|---|
| Exsil Avanti ODS, 1.5 µm | 5136628. |
| Exsil Avanti ODS, 3 µm | 5136625. |
| Exsil Avanti ODS, 5 µm | 5136635. |
| Exsil Avanti ODS, 10 µm | 5136757. |