Exsil Avanti Phenyl is a high-efficiency phenyl-bonded silica stationary phase developed for selective reversed-phase HPLC and UHPLC separations, particularly of aromatic and conjugated compounds. By combining hydrophobic retention with enhanced π–π interaction capability, this phase provides complementary selectivity to traditional C18 or C8 materials.
The aromatic phenyl surface enables additional interaction mechanisms such as π–π stacking, dipole interactions, and shape recognition effects. This makes Exsil Avanti Phenyl especially suitable for structurally related aromatic analytes, isomer separations, polyaromatic compounds, pharmaceuticals, and heterocyclic molecules. The balanced retention profile allows efficient resolution without excessive analysis time. Manufactured on the advanced Exsil Avanti high-purity spherical silica platform, the phase delivers excellent mechanical strength, uniform packing quality, and reproducible chromatographic performance under both HPLC and UHPLC conditions. The optimized surface chemistry reduces unwanted secondary interactions, resulting in sharp peaks and consistent retention behavior across gradient and isocratic methods.
Exsil Avanti Phenyl combines aromatic interaction capability with high-efficiency silica technology — delivering enhanced selectivity, reproducible performance, and precise reversed-phase separations for complex organic analytes.
Phenyl-bonded silica phase with enhanced π–π selectivity
Complementary selectivity to C18 and C8 phases
Ideal for aromatic, conjugated, and heterocyclic compounds
High efficiency and excellent peak symmetry
Robust spherical silica for long column lifetime
Suitable for analytical and preparative reversed-phase HPLC
Separation of aromatic pharmaceuticals and impurities
Isomer resolution of structurally related compounds
Analysis of polyaromatic hydrocarbons and heterocycles
Environmental and food safety testing
Method development requiring alternative RP selectivity
| Particle Sizes |
|
|---|---|
| Pore Size | 130 Å |
| Surface Area | 195 m²/g |
| Phase/Modification | Phenyl |
| Particle Type | |
| Separation Mode | |
| USP Code | |
| Endcapping | No |
| Carbonload | 4 % |
| pH Range | 2 - 8 |
| Phase | Material Number |
|---|---|
| Exsil Avanti Phenyl, 3 µm | 5136633. |
| Exsil Avanti Phenyl, 5 µm | 5136634. |