Exsil Avanti Phenyl

Aromatic Selectivity for Advanced Reversed-Phase HPLC and UHPLC

Exsil Avanti Phenyl is a high-efficiency phenyl-bonded silica stationary phase developed for selective reversed-phase HPLC and UHPLC separations, particularly of aromatic and conjugated compounds. By combining hydrophobic retention with enhanced π–π interaction capability, this phase provides complementary selectivity to traditional C18 or C8 materials.

The aromatic phenyl surface enables additional interaction mechanisms such as π–π stacking, dipole interactions, and shape recognition effects. This makes Exsil Avanti Phenyl especially suitable for structurally related aromatic analytes, isomer separations, polyaromatic compounds, pharmaceuticals, and heterocyclic molecules. The balanced retention profile allows efficient resolution without excessive analysis time. Manufactured on the advanced Exsil Avanti high-purity spherical silica platform, the phase delivers excellent mechanical strength, uniform packing quality, and reproducible chromatographic performance under both HPLC and UHPLC conditions. The optimized surface chemistry reduces unwanted secondary interactions, resulting in sharp peaks and consistent retention behavior across gradient and isocratic methods.

Exsil Avanti Phenyl combines aromatic interaction capability with high-efficiency silica technology — delivering enhanced selectivity, reproducible performance, and precise reversed-phase separations for complex organic analytes.

Key Features

  • Phenyl-bonded silica phase with enhanced π–π selectivity

  • Complementary selectivity to C18 and C8 phases

  • Ideal for aromatic, conjugated, and heterocyclic compounds

  • High efficiency and excellent peak symmetry

  • Robust spherical silica for long column lifetime

  • Suitable for analytical and preparative reversed-phase HPLC

Typical Applications

  • Separation of aromatic pharmaceuticals and impurities

  • Isomer resolution of structurally related compounds

  • Analysis of polyaromatic hydrocarbons and heterocycles

  • Environmental and food safety testing

  • Method development requiring alternative RP selectivity

Specifications

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Particle Sizes
  • 3 µm
  • 5 µm
Pore Size 130 Å
Surface Area 195 m²/g
Phase/Modification Phenyl
Particle Type
Separation Mode
USP Code
Endcapping No
Carbonload 4 %
pH Range 2 - 8

Material Numbers

Phase Material Number
Exsil Avanti Phenyl, 3 µm 5136633.
Exsil Avanti Phenyl, 5 µm 5136634.
Exsil Avanti ODS Exsil Avanti SAX

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