Exsil Avanti SAX is a high-efficiency strong anion exchange (SAX) silica stationary phase engineered for precise and reproducible ion-exchange chromatography in HPLC and UHPLC systems. Featuring permanently charged quaternary ammonium functional groups, this phase provides stable and powerful electrostatic retention of negatively charged analytes across a broad pH range.
The optimized surface chemistry ensures high binding capacity and controlled selectivity for organic acids, nucleotides, nucleic acids, acidic pharmaceuticals, and other anionic compounds. Thanks to its robust spherical silica backbone and uniform particle distribution, Exsil Avanti SAX delivers excellent efficiency, consistent peak shape, and long column lifetime — even under high-pressure UHPLC conditions. Designed for modern analytical workflows, the phase supports aqueous buffer systems and gradient elution using salt concentration or pH modulation. The strong and stable ion-exchange functionality enables reliable separation of complex mixtures, making it ideal for pharmaceutical, environmental, biochemical, and food safety laboratories.
Exsil Avanti SAX combines high-capacity strong anion exchange chemistry with advanced silica technology — delivering precise, reliable, and high-resolution ion-exchange separations for demanding analytical applications.
Strong anion exchange (SAX) functionality with quaternary ammonium groups
High-capacity retention of negatively charged analytes
Stable performance over a wide pH range
High efficiency and reproducible chromatographic behavior
Mechanically robust spherical silica particles
Compatible with aqueous buffers and gradient ion-exchange methods
Separation of organic acids and acidic pharmaceuticals
Ion-exchange HPLC of nucleotides and nucleic acids
Analysis of anionic impurities and metabolites
Biochemical and environmental sample testing
Method development in ion-exchange chromatography
| Particle Size |
|
|---|---|
| Pore Size | 130 Å |
| Surface Area | 195 m²/g |
| Phase/Modification | SAX |
| Particle Type | |
| Separation Mode | |
| USP Code | |
| Endcapping | No |
| Carbonload | 5 % |
| pH Range | 2 - 8 |
| Phase | Material Number |
|---|---|
| Exsil Avanti SAX, 5 µm | 5136636. |