GromSil 100 NP-1

Unmodified Silica Column for Classical Normal-Phase and Adsorption Chromatography

GromSil 100 NP-1 is a high-purity, fully porous silica column from Dr. Maisch HPLC GmbH, featuring a 100 Å pore size and an unmodified (bare) surface. Designed for traditional normal-phase and adsorption chromatography, this phase provides strong polar interactions through active silanol groups, allowing effective separation of polar, non-derivatized compounds such as isomers, organic acids, and amines.

Its consistent surface activity, mechanical robustness, and high batch-to-batch reproducibility make it a reliable choice for polar separations and orthogonal method development.

This bare silica phase from Dr. Maisch HPLC GmbH provides robust and selective performance — ideal for laboratories applying classical polarity-based separation techniques.

Key Features:

  • Unmodified silica surface – USP L3 classification

  • Fully porous silica with 100 Å pore size

  • Strong polar retention via silanol interactions

  • Suitable for normal-phase and dry-loading workflows

  • Available in 3 µm, 5 µm, and 10 µm particle sizes

Typical Applications:

  • Isomer separations, sugar derivatives, and polar small molecules

  • Normal-phase chromatography with non-aqueous eluents

  • Method development complementary to reversed-phase LC

  • Adsorption chromatography and sample fractionation

Specifications

Request Product
Particle Sizes
  • 3 µm
  • 5 µm
  • 10 µm
Pore Size 100 Å
Phase/Modification Si
Particle Type
Separation Modes
USP Code
Endcapping No
pH Range 2 - 8

Applications

Material Numbers

Phase Material Number
GromSil 100 NP-1, 3 µm GSNP10310.
GromSil 100 NP-1, 5 µm GSNP10510.
GromSil 100 NP-1, 10 µm GSNP11010.
GromSil 100 Amino-1 PR GromSil 100 NP-4

Any questions?
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info@dr-maisch.com +49 7073 5035 7

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