GromSil 100 NP-4 is a fully porous, unmodified silica HPLC column from Dr. Maisch HPLC GmbH, featuring a 100 Å pore size and optimized surface activity. This normal-phase column provides strong polar retention via active silanol groups, enabling effective separation of polar analytes such as isomers, organic acids, and functionalized small molecules.
The phase offers stable performance with non-aqueous mobile phases and is ideal for adsorption-based workflows, orthogonal method development, and preparative purification of polar compounds.
This silica-based normal-phase column from Dr. Maisch HPLC GmbH delivers robust retention and high-resolution performance — ideal for challenging polar compound separations and adsorption chromatography.
Bare silica phase – USP L3 classification
Fully porous, high-purity silica with 100 Å pore size
Strong polar interactions for normal-phase and dry-load applications
Reproducible retention and high mechanical stability
Available in 3 µm, 5 µm, and 10 µm particle sizes
Normal-phase chromatography of polar organics, acids, and alcohols
Separation of isomers and closely related small molecules
Sample clean-up and dry-loading in preparative LC
Orthogonal selectivity to reversed-phase and HILIC methods
| Particle Size |
|
|---|---|
| Pore Size | 100 Å |
| Phase/Modification | Si |
| Particle Type | |
| Separation Modes | |
| USP Code | |
| Endcapping | No |
| pH Range | 2 - 8 |
| Phase | Material Number |
|---|---|
| GromSil 100 NP-4, 5 µm | GSNP40510. |