GromSil 100 Octyl-1 B is a reversed-phase HPLC column from Dr. Maisch HPLC GmbH, packed with fully porous, high-purity silica featuring a 100 Å pore size and bonded with octyl (C8) ligands. This phase offers moderate hydrophobic retention compared to C18, making it ideal for analytes that are excessively retained or poorly resolved on longer-chain phases.
Its balanced retention profile and sharp peak shape make it well suited for method development, impurity profiling, and routine analysis of small to medium-sized compounds in pharmaceutical and chemical applications.
This C8 phase from Dr. Maisch HPLC GmbH combines reliable reversed-phase performance with flexible retention – ideal for compounds requiring faster elution or complementary selectivity to C18.
Octyl (C8) bonded phase – USP L7 classification
Fully porous silica with 100 Å pore size
Moderate hydrophobic retention for faster elution of strongly retained analytes
High column efficiency and reproducible performance
Available in 3 µm, 5 µm, and 10 µm particle sizes
APIs, excipients, and impurities with medium hydrophobicity
Method development requiring selective retention adjustment
LC-MS and UV detection in reversed-phase workflows
Routine pharmaceutical and chemical analysis
| Particle Sizes |
|
|---|---|
| Pore Size | 100 Å |
| Phase/Modification | C8 |
| Particle Type | |
| Separation Mode | |
| USP Code | |
| pH Range | 2 - 8 |
| Phase | Material Number |
|---|---|
| GromSil 100 Octyl-1 B, 3 µm | GSOC10310. |
| GromSil 100 Octyl-1 B, 5 µm | GSOC10510. |