GromSil 100 Octyl-2 AB is a reversed-phase HPLC column from Dr. Maisch HPLC GmbH, packed with fully porous, high-purity silica (100 Å pore size) and bonded with octyl (C8) ligands. The phase features an advanced endcapping (AB) process that reduces silanol activity and improves peak shape, especially for basic and ionizable analytes. It provides moderate hydrophobic retention, ideal for compounds that elute too slowly on C18 materials.
This column is particularly useful in pharmaceutical quality control and method development where reproducibility and peak symmetry are critical.
This endcapped C8 phase from Dr. Maisch HPLC GmbH delivers robust performance and refined peak symmetry — ideal for demanding reversed-phase applications involving basic or tailing-prone compounds.
Octyl (C8) bonded reversed-phase phase with advanced endcapping – USP L7
Fully porous silica with 100 Å pore size
Enhanced peak shape for basic and polar analytes
Moderate hydrophobicity for faster elution than C18 phases
Available in 3 µm, 5 µm, and 10 µm particle sizes
Basic drug substances, intermediates, and polar small molecules
Reversed-phase separations in pharmaceutical and fine chemical analysis
LC-MS and UV detection of moderately hydrophobic analytes
Method development requiring high reproducibility and controlled retention
| Particle Sizes |
|
|---|---|
| Pore Size | 100 Å |
| Phase/Modification | C8 |
| Particle Type | |
| Separation Mode | |
| USP Code | |
| pH Range | 2 - 8 |
| Phase | Material Number |
|---|---|
| GromSil 100 Octyl-2 AB, 3 µm | GSOC20310. |
| GromSil 100 Octyl-2 AB, 5 µm | GSOC20510. |