GromSil 120 ODS-4 HE is a reversed-phase HPLC column from Dr. Maisch HPLC GmbH, based on fully porous, high-purity silica with a 120 Å pore size and bonded with octadecyl (C18) ligands. This high-end (HE) phase features advanced endcapping and ultra-clean surface deactivation, resulting in outstanding peak symmetry, low bleed behavior, and exceptional batch-to-batch reproducibility — even for basic or tailing-prone analytes.
Developed for regulated environments and LC-MS applications, this phase is particularly well suited for pharmaceutical method validation, stability testing, and high-resolution impurity profiling.
With superior surface chemistry and reproducibility, GromSil 120 ODS-4 HE from Dr. Maisch HPLC GmbH is the column of choice for demanding reversed-phase separations where accuracy, stability, and peak integrity are essential.
Octadecyl (C18) bonded phase with high-end surface treatment – USP L1
Fully porous silica with 120 Å pore size
Outstanding peak shape for basic, polar, and neutral analytes
Ultra-low silanol activity and high batch consistency
Available in 3 µm, 5 µm, and 10 µm particle sizes
LC-MS and UV analysis of APIs, impurities, and degradation products
Validated methods in GMP and regulated laboratories
High-resolution profiling of basic and ionizable compounds
Robust reversed-phase separations in pharmaceutical QC and R&D
| Particle Sizes |
|
|---|---|
| Pore Size | 120 Å |
| Phase/Modification | C18 |
| Particle Type | |
| Separation Modes | |
| USP Code | |
| Endcapping | Yes |
| pH Range | 2 - 8 |
| Phase | Material Number |
|---|---|
| GromSil 120 ODS-4 HE, 3 µm | GSOD40312. |
| GromSil 120 ODS-4 HE, 5 µm | GSOD40512. |
| GromSil 120 ODS-4 HE, 7 µm | GSOD40712. |
| GromSil 120 ODS-4 HE, 10 µm | GSOD41012. |