GromSil 300 Butyl-2 FE is a reversed-phase HPLC column from Dr. Maisch HPLC GmbH, packed with fully porous, high-purity silica featuring a 300 Å pore size and bonded with butyl (C4) ligands. The fully endcapped surface (FE) minimizes residual silanol activity, ensuring improved peak symmetry and reproducibility—especially for basic and ionizable analytes.
Its wide-pore structure supports efficient mass transfer and analyte accessibility, making this phase particularly suitable for peptides, protein fragments, and hydrophobic biomolecules that benefit from moderate retention and enhanced resolution.
Combining wide-pore accessibility with excellent peak performance, GromSil 300 Butyl-2 FE from Dr. Maisch HPLC GmbH is the ideal choice for reversed-phase applications requiring moderate retention and optimal performance for large, hydrophobic molecules.
Butyl (C4) bonded reversed-phase phase with full endcapping – USP L26
Fully porous silica with 300 Å pore size for high-molecular-weight analytes
Mild hydrophobic retention for fast, efficient separations
Improved peak shape and reduced tailing for basic compounds
Available in 5 µm and 10 µm particle sizes
Peptides, protein fragments, and lipophilic therapeutic compounds
LC-MS and UV workflows for large or strongly retained analytes
Method development for high-throughput reversed-phase separations
Bioanalytical and pharmaceutical research involving complex samples
| Particle Sizes |
|
|---|---|
| Pore Size | 300 Å |
| Phase/Modification | C4 |
| Particle Type | |
| Separation Mode | |
| USP Code | |
| Endcapping | Yes |
| pH Range | 2 - 8 |
| Phase | Material Number |
|---|---|
| GromSil 300 Butyl-2 FE, 3 µm | GSBU20330. |
| GromSil 300 Butyl-2 FE, 5 µm | GSBU20530. |