GromSil 300 ODS-5 ST is a reversed-phase HPLC column from Dr. Maisch HPLC GmbH, packed with fully porous, high-purity silica featuring a 300 Å pore size and bonded with octadecyl (C18) ligands. With standard endcapping (ST), this phase provides strong hydrophobic retention and consistent peak shape, making it ideal for the separation of large or structurally complex compounds such as peptides, proteins, and hydrophobic drug molecules.
The wide-pore architecture ensures optimal accessibility and mass transfer for high-molecular-weight analytes, supporting both LC-MS and UV detection in pharmaceutical and bioanalytical workflows.
Offering reliable performance and excellent retention for large analytes, GromSil 300 ODS-5 ST from Dr. Maisch HPLC GmbH is the ideal choice for reversed-phase chromatography involving high-molecular-weight or strongly retained compounds.
Octadecyl (C18) bonded reversed-phase phase with standard endcapping – USP L1
Fully porous silica with 300 Å pore size for large and hydrophobic compounds
Strong hydrophobic interaction for robust retention and resolution
High mechanical stability and batch-to-batch reproducibility
Available in 5 µm and 10 µm particle sizes
Peptides, proteins, glycoproteins, and lipophilic drug substances
Reversed-phase LC-MS and UV methods in pharmaceutical analysis
High-resolution separations of structurally complex biomolecules
Method development for analytes requiring wide-pore access
| Particle Sizes |
|
|---|---|
| Pore Size | 300 Å |
| Phase/Modification | C18 |
| Particle Type | |
| Separation Mode | |
| USP Code | |
| pH Range | 2 - 8 |
| Phase | Material Number |
|---|---|
| GromSil 300 ODS-5 ST, 3 µm | GSOD50330. |
| GromSil 300 ODS-5 ST, 5 µm | GSOD50530. |
| GromSil 300 ODS-5 ST, 10 µm | GSOD51030. |