ReproSil DIBS-C18 is a silica-based HPLC column with a long-chain octadecyl bonded phase, specifically tailored for the Direct Injection of Biological Samples (DIBS). The C18 modification provides strong hydrophobic retention, making it especially effective for the separation of hydrophobic peptides, proteins, and small biomolecules in complex biological matrices. The specialized DIBS surface minimizes matrix interferences and reduces non-specific binding, enabling reproducible direct injection of biological fluids such as plasma and serum without extensive sample preparation. With its durable silica backbone and optimized bonding chemistry, ReproSil DIBS-C18 combines high efficiency with robust performance in bioanalytical applications.
ReproSil DIBS-C18 delivers strong hydrophobic selectivity with robust silica stability – the reliable solution for efficient and reproducible direct injection analysis of biological samples.
Silica-based stationary phase with octadecyl (C18) bonding for DIBS
Strong hydrophobic retention for proteins, peptides, and hydrophobic metabolites
Designed for direct injection of plasma, serum, and other biological matrices
Reduces matrix effects and non-specific adsorption
High efficiency, robustness, and reproducibility
Manufactured and QC-tested by Dr. Maisch HPLC GmbH
Available in 20 µm particle size
Bioanalysis of hydrophobic peptides, proteins, and metabolites
Direct injection of complex biological fluids
Pharmaceutical research and clinical studies
Method development for bioanalytical HPLC
| Particle Size |
|
|---|---|
| Pore Size | 120 Å |
| Phase/Modification | C18 |
| Particle Type | |
| Separation Modes | |
| pH Range | 2 to 8 |
| Phase | Material Number |
|---|---|
| ReproSil DIBS-C18, 20 µm | dibs20.90. |