ReproSil Gold 300 C8 from Dr. Maisch HPLC GmbH is a high-purity silica HPLC column with a 300 Å pore size and an octyl bonded phase. This medium-chain stationary phase offers moderate hydrophobic retention, allowing faster elution than C18 while maintaining excellent resolution for large biomolecules such as proteins, enzymes, and glycoproteins. The extra-wide pore size ensures efficient mass transfer and optimal accessibility for high-molecular-weight analytes, while delivering sharp peak shapes, high separation efficiency, and reproducible retention.
ReproSil Gold 300 C8 columns from Dr. Maisch HPLC GmbH combine balanced retention with wide-pore accessibility – the versatile choice for large biomolecule chromatography in HPLC.
Fully porous, ultra-pure silica with 300 Å pore size
C8 bonding – USP L7 classification
Balanced hydrophobic retention for faster separations than C18
Optimized for proteins, enzymes, and large biomolecules
Manufactured and QC-tested by Dr. Maisch HPLC GmbH
Available in 3 µm, 5 µm, and 10 µm particle sizes
Protein and peptide separations in proteomics and biopharma
Biopharmaceutical quality control and method validation
Gradient HPLC of large and hydrophobic biomolecules
Method development requiring moderate retention
| Particle Sizes |
|
|---|---|
| Pore Size | 300 Å |
| Surface Area | 100 m²/g |
| Phase/Modification | C8 |
| Particle Type | |
| Separation Mode | |
| USP Code | |
| Endcapping | Yes |
| Carbonload | 5 % |
| pH Range | 2 to 9 |
| Phase | Material Number |
|---|---|
| ReproSil Gold 300 C8, 3 µm | r33.8g. |
| ReproSil Gold 300 C8, 5 µm | r35.8g. |
| ReproSil Gold 300 C8, 10 µm | r30.8g. |