ReproSil-Pur 120 C18 ace-EPS is a silica-based HPLC column with octadecyl bonded chemistry and a polar-embedded group, built on high-purity 120 Å silica. The embedded polar functionality reduces silanol interactions, improving peak symmetry for basic analytes, while maintaining strong hydrophobic retention for nonpolar compounds.
This dual retention mechanism makes ReproSil-Pur 120 C18 ace-EPS especially versatile for complex mixtures and stability-indicating assays, where both hydrophobic and polar interactions are required. The robust bonding chemistry ensures reproducibility and long operational lifetimes.
ReproSil-Pur 120 C18 ace-EPS provides robust hydrophobic retention with enhanced polar selectivity – the reliable choice for laboratories performing complex reversed-phase HPLC separations.
High-purity silica with octadecyl (C18) bonded chemistry and polar-embedded group
120 Å pore size optimized for small to medium-sized molecules
Balanced retention combining hydrophobic and polar interactions
Reduced silanol activity for improved peak symmetry of basic analytes
Available particle sizes: 3 µm, 5 µm
Pharmaceutical impurity profiling and forced degradation studies
Biochemical analysis of basic drugs, polar metabolites, and mixed analytes
Food and beverage testing of hydrophobic and polar compounds
Environmental monitoring of pollutants requiring orthogonal selectivity
Method development requiring versatile reversed-phase selectivity
| Particle Sizes |
|
|---|---|
| Pore Size | 120 Å |
| Surface Area | 300 m²/g |
| Phase/Modification | Amid-C18 |
| Particle Type | |
| Separation Modes | |
| USP Code | |
| Endcapping | Yes |
| Carbonload | 12.5 % |
| pH Range | 2 to 8 |
| Phase | Material Number |
|---|---|
| ReproSil-Pur 120-C18 ace-EPS, 3 µm | r13.9ep. |
| ReproSil-Pur 120-C18 ace-EPS, 5 µm | r15.9ep. |