ReproSil-Pur 120 C18-AQ

Water-Stable C18 HPLC Column for Polar Analytes

ReproSil-Pur 120 C18-AQ is a silica-based HPLC column with octadecyl bonded chemistry, specially modified for full aqueous compatibility. Built on high-purity 120 Å silica, this phase is designed to maintain stability and reproducibility under 100% aqueous mobile phases, avoiding phase collapse often observed with conventional C18 columns.

The hydrophilic endcapping ensures retention of highly polar analytes while maintaining strong hydrophobic interactions for nonpolar compounds. This makes ReproSil-Pur 120 C18-AQ a versatile tool for laboratories requiring reliable separations of complex mixtures across a wide polarity range.

ReproSil-Pur 120 C18-AQ combines robust hydrophobic retention with full aqueous stability – the dependable choice for laboratories analyzing polar compounds in reversed-phase HPLC.

Key Features:

  • High-purity silica with octadecyl (C18) bonded chemistry

  • Water-stable modification prevents phase collapse in 100% aqueous eluents

  • Enhanced retention of polar compounds with hydrophilic endcapping

  • Robust bonding for reproducibility and long operational lifetimes

  • Available particle sizes: 1.9 µm - 20 µm

Typical Applications:

  • Pharmaceutical analysis of polar drugs and hydrophilic metabolites

  • Biochemical separations of peptides, nucleosides, and polar biomolecules

  • Food and beverage testing of sugars, organic acids, and polar additives

  • Environmental monitoring of water-soluble pollutants

  • Method development requiring reversed-phase selectivity under aqueous conditions

Specifications

Request Product
Particle Sizes
  • 1.9 µm
  • 2.4 µm
  • 3 µm
  • 4 µm
  • 5 µm
  • 7 µm
  • 10 µm
  • 15 µm
  • 20 µm
Pore Size 120 Å
Surface Area 300 m²/g
Phase/Modification C18
Particle Type
Separation Mode
USP Code
Endcapping Yes
Carbonload 15 %
pH Range 2 to 8

Applications

Material Numbers

Phase Material Number
ReproSil-Pur 120 C18-AQ, 1.9 µm r119.aq.
ReproSil-Pur 120 C18-AQ, 2.4 µm r124.aq.
ReproSil-Pur 120 C18-AQ, 3 µm r13.aq.
ReproSil-Pur 120 C18-AQ, 4 µm r14.aq.
ReproSil-Pur 120 C18-AQ, 5 µm r15.aq.
ReproSil-Pur 120 C18-AQ, 7 µm r17.aq.
ReproSil-Pur 120 C18-AQ, 10 µm r10.aq.
ReproSil-Pur 120 C18-AQ, 15 µm r115.aq.
ReproSil-Pur 120 C18-AQ, 20 µm r120.aq.
ReproSil-Pur 120-C18 ace-EPS ReproSil-Pur 120 C18-SH

Any questions?
We are here to help you.

info@dr-maisch.com +49 7073 5035 7

Follow us