ReproSil-Pur 120 C8-SH is a silica-based HPLC column featuring an endcapped octyl bonded phase with enhanced shape selectivity. Developed on high-purity spherical silica with a 120 Å pore size, this phase combines balanced hydrophobic retention with the ability to discriminate between analytes based on molecular geometry.
The endcapped C8 surface minimizes residual silanol interactions, ensuring sharp peak shapes and high reproducibility even for basic or polar analytes. The integrated shape-selective properties provide improved resolution for isomers and structurally related compounds, making ReproSil-Pur 120 C8-SH particularly suited for advanced pharmaceutical, biochemical, and chemical analyses.
ReproSil-Pur 120 C8-SH combines controlled hydrophobicity with advanced shape selectivity – the reliable choice for precise and reproducible separations of complex analytes in HPLC.
Endcapped silica-based stationary phase with C8 bonding and shape selectivity
Balanced hydrophobic retention and reduced silanol activity
Enhanced separation of isomers and structurally related analytes
High reproducibility and long column lifetime
Suitable for analytical and preparative workflows
Available particle sizes: 3 µm, 5 µm
Resolution of structural and positional isomers
Pharmaceutical impurity profiling and stability studies
Analysis of moderately hydrophobic biomolecules and metabolites
Method development requiring complementary selectivity to standard C8 or C18 phases
| Particle Sizes |
|
|---|---|
| Pore Size | 120 Å |
| Surface Area | 300 m²/g |
| Phase/Modification | C8 |
| Particle Type | |
| Separation Mode | |
| USP Code | |
| Endcapping | Yes |
| Carbonload | 10 % |
| pH Range | 1 to 8 |
| Phase | Material Number |
|---|---|
| ReproSil-Pur 120 C8-SH, 3 µm | r13.8sh. |
| ReproSil-Pur 120 C8-SH, 5 µm | r15.8sh. |