ReproSil-Pur 120 C18-SH is a silica-based HPLC column featuring an endcapped octadecyl bonded phase with enhanced shape selectivity. Built on high-purity spherical silica with a 120 Å pore size, this phase combines strong hydrophobic retention with the ability to distinguish analytes based on their molecular shape and structural differences.
The endcapping process effectively reduces residual silanol activity, ensuring sharp peak shapes and reproducible retention even for basic or polar analytes. The integrated shape-selective properties enhance the separation of isomers, aromatic compounds, and structurally similar molecules, making ReproSil-Pur 120 C18-SH an excellent choice for demanding pharmaceutical, biochemical, and chemical analyses.
ReproSil-Pur 120 C18-SH offers strong hydrophobic retention combined with refined shape recognition – the reliable choice for precise and reproducible HPLC separations of complex analytes.
Endcapped silica-based stationary phase with C18 bonding and shape selectivity
Strong hydrophobic retention with reduced silanol interactions
Improved resolution of isomers and structurally related analytes
High mechanical stability and reproducibility for consistent performance
Suitable for analytical and preparative workflows
Available particle sizes: 3 µm, 5 µm
Separation of structural and positional isomers
Pharmaceutical impurity profiling and stability-indicating assays
Analysis of hydrophobic biomolecules, metabolites, and aromatic compounds
Method development requiring enhanced shape and hydrophobic selectivity
| Particle Sizes |
|
|---|---|
| Pore Size | 120 Å |
| Surface Area | 300 m²/g |
| Phase/Modification | C18 |
| Particle Type | |
| Separation Mode | |
| USP Code | |
| Endcapping | Yes |
| Carbonload | 17 % |
| pH Range | 2 to 8 |
| Phase | Material Number |
|---|---|
| ReproSil-Pur 120 C18-SH, 3 µm | r13.9sh. |
| ReproSil-Pur 120 C18-SH, 5 µm | r15.9sh. |