ReproSil-Pur 120 C8

Medium-Chain Alkyl HPLC Column for Versatile Separations

ReproSil-Pur 120 C8 is a silica-based HPLC column with octyl bonded chemistry on high-purity 120 Å silica. Offering medium hydrophobic retention, it provides shorter analysis times than C18 phases while maintaining excellent peak symmetry and reproducibility. This makes it a versatile option for both routine and method development applications.

The 120 Å pore size ensures efficient separations of small to medium-sized molecules, while the robust bonding chemistry guarantees long column lifetimes and consistent performance. ReproSil-Pur 120 C8 is widely used in pharmaceutical, biochemical, food, and environmental laboratories.

ReproSil-Pur 120 C8 delivers balanced hydrophobic retention with robust reproducibility – the reliable choice for laboratories performing versatile reversed-phase HPLC separations.

Key Features:

  • High-purity silica with octyl (C8) bonded chemistry

  • 120 Å pore size optimized for small to medium-sized molecules

  • Medium hydrophobic retention with faster elution than C18

  • Robust bonding ensures reproducibility and long column lifetime

  • Available particle sizes: 3 µm - 20 µm

Typical Applications:

  • Pharmaceutical impurity profiling and stability testing

  • Biochemical separations of moderately hydrophobic drugs and metabolites

  • Food and beverage testing of additives, preservatives, and contaminants

  • Environmental monitoring of organic pollutants

  • Method development requiring complementary selectivity to C18

Specifications

Request Product
Particle Sizes
  • 3 µm
  • 5 µm
  • 10 µm
  • 20 µm
Pore Size 120 Å
Surface Area 300 m²/g
Phase/Modification C8
Particle Type
Separation Mode
USP Code
Endcapping Yes
Carbonload 9 %
pH Range 2 to 8

Applications

Material Numbers

Phase Material Number
ReproSil-Pur 120 C8, 3 µm r13.8e.
ReproSil-Pur 120 C8, 5 µm r15.8e.
ReproSil-Pur 120 C8, 10 µm r10.8e.
ReproSil-Pur 120 C8, 20 µm r120.8e.
ReproSil-Pur 120 C4 ReproSil-Pur 120 C8-SH

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