ReproSil-Pur 200 ODS-3

Wide-Pore C18 HPLC Column for Peptides and Medium Biomolecules

ReproSil-Pur 200 ODS-3 is a silica-based HPLC column with octadecyl bonded chemistry on high-purity 200 Å silica. The wide-pore design ensures excellent accessibility for larger analytes such as peptides and small proteins, while the C18 bonding delivers strong hydrophobic retention and reproducible separations.

Compared to narrow-pore columns, ReproSil-Pur 200 ODS-3 offers improved performance for biomolecules, providing sharp peak shapes and robust lifetimes under demanding chromatographic conditions. It is particularly well suited for biopharmaceutical, biochemical, and pharmaceutical laboratories.

ReproSil-Pur 200 ODS-3 provides robust C18 retention with wide-pore accessibility – the dependable choice for laboratories analyzing peptides and medium-sized biomolecules by HPLC.

Key Features:

  • High-purity silica with octadecyl (C18, ODS) bonded chemistry

  • 200 Å wide-pore structure for peptides and medium biomolecules

  • Strong hydrophobic retention with sharp and symmetrical peak shapes

  • Robust bonding chemistry ensures reproducibility and long lifetime

  • Available particle sizes: 3 µm, 5 µm, 10 µm, 15 µm

Typical Applications:

  • Peptide mapping and biopharmaceutical analysis

  • Separation of small proteins, glycopeptides, and biomolecular fragments

  • Pharmaceutical analysis of hydrophobic drugs and metabolites

  • Food and beverage testing for proteinaceous and peptide compounds

  • Method development requiring wide-pore reversed-phase selectivity

Specifications

Request Product
Particle Sizes
  • 3 µm
  • 5 µm
  • 10 µm
  • 15 µm
Pore Size 200 Å
Surface Area 200 m²/g
Phase/Modification C18
Particle Type
Separation Mode
USP Code
Endcapping Yes
Carbonload 12 %
pH Range 2 to 8

Material Numbers

Phase Material Number
ReproSil-Pur 200 ODS-3, 3 µm r23.93.
ReproSil-Pur 200 ODS-3, 5 µm r25.93.
ReproSil-Pur 200 ODS-3, 10 µm r20.93.
ReproSil-Pur 200 ODS-3, 15 µm r215.93.
ReproSil-Pur 200 Diol ReproSil-Pur 200 Si

Any questions?
We are here to help you.

info@dr-maisch.com +49 7073 5035 7

Follow us