ReproSil-Pur 300 ODS-3 is a silica-based HPLC column with octadecyl bonded chemistry on high-purity 300 Å silica. The wide-pore design ensures excellent accessibility for proteins, peptides, and other large biomolecules, while the C18 bonding provides strong hydrophobic retention for reliable and reproducible separations.
Compared to narrow-pore ODS columns, ReproSil-Pur 300 ODS-3 improves mass transfer for macromolecules, delivering sharp peak shapes and consistent results even under demanding gradient or elevated temperature conditions. It is a proven choice for biopharmaceutical, biochemical, and proteomic applications.
ReproSil-Pur 300 ODS-3 delivers wide-pore accessibility with strong C18 retention – the dependable choice for laboratories analyzing proteins and peptides in reversed-phase HPLC.
High-purity silica with octadecyl (C18, ODS) bonded chemistry
300 Å wide-pore structure optimized for proteins, peptides, and biomolecules
Strong hydrophobic retention with excellent reproducibility
Robust bonding ensures long operational lifetimes under demanding conditions
Available particle sizes: 3 µm, 5 µm, 10 µm
Biopharmaceutical analysis of therapeutic proteins and peptides
Proteomics applications requiring wide-pore reversed-phase chromatography
Peptide mapping and protein fragment analysis
Food and biochemical testing of proteinaceous and peptide-based compounds
Method development requiring robust C18 selectivity for large biomolecules
| Particle Sizes |
|
|---|---|
| Pore Size | 300 Å |
| Surface Area | 100 m²/g |
| Phase/Modification | C18 |
| Particle Type | |
| Separation Mode | |
| USP Code | |
| Endcapping | Yes |
| Carbonload | 9 % |
| pH Range | 2 to 8 |
| Phase | Material Number |
|---|---|
| ReproSil-Pur 300 ODS-3, 3 µm | r33.93. |
| ReproSil-Pur 300 ODS-3, 5 µm | r35.93. |
| ReproSil-Pur 300 ODS-3, 10 µm | r30.93. |