ReproSil-Pur Basic C18 is a silica-based HPLC column with octadecyl bonded chemistry on high-purity silica, specifically engineered for the separation of basic and polar compounds. The optimized surface treatment minimizes silanol interactions, delivering sharp peak shapes and excellent reproducibility, even for challenging analytes such as amines, alkaloids, and cationic pharmaceuticals.
The C18 bonding provides strong hydrophobic retention and broad applicability across a wide range of analytes, making ReproSil-Pur Basic C18 the most versatile phase in this series. Robust bonding chemistry ensures long operational lifetimes and stable performance under routine and demanding chromatographic conditions.
ReproSil-Pur Basic C18 delivers strong hydrophobic retention with optimized performance for basic compounds – the reliable choice for laboratories requiring versatile and reproducible HPLC separations.
High-purity silica with octadecyl (C18) bonded chemistry
Optimized surface treatment for basic and polar analytes
Strong hydrophobic retention for broad applicability
Reduced silanol activity ensures improved peak symmetry
Available particle sizes: 1.9 µm - 15 µm
Pharmaceutical analysis of basic drugs, alkaloids, and amines
Biochemical separations of hydrophobic and polar metabolites
Food and beverage testing of nitrogen-containing compounds and hydrophobic additives
Environmental monitoring of cationic and polar pollutants
Method development requiring robust C18 selectivity for basic analytes
| Particle Sizes |
|
|---|---|
| Pore Size | 100 Å |
| Surface Area | 450 m²/g |
| Phase/Modification | C18 |
| Particle Type | |
| Separation Mode | |
| USP Code | |
| Endcapping | Yes |
| Carbonload | 17 % |
| pH Range | 2 to 8 |
| Phase | Material Number |
|---|---|
| ReproSil-Pur Basic-C18, 1.9 µm | r119.b9. |
| ReproSil-Pur Basic-C18, 2.5 µm | r125.b9. |
| ReproSil-Pur Basic-C18, 3 µm | r13.b9. |
| ReproSil-Pur Basic-C18, 4 µm | r14.b9. |
| ReproSil-Pur Basic-C18, 5 µm | r15.b9. |
| ReproSil-Pur Basic-C18, 10 µm | r10.b9. |
| ReproSil-Pur Basic-C18, 15 µm | r115.b9. |