ReproSil-Pur Basic-C8 is a silica-based HPLC column with octyl bonded chemistry on high-purity silica. Offering medium hydrophobic retention, it provides shorter analysis times than C18 phases while maintaining excellent resolution and peak symmetry.
As part of the ReproSil-Pur Basic series, the surface is specially optimized for basic and polar compounds. Reduced silanol activity minimizes peak tailing of amines, alkaloids, and other challenging analytes, ensuring reproducible and robust performance in routine and advanced separations.
ReproSil-Pur Basic-C8 combines balanced hydrophobic retention with optimized performance for basic analytes – the dependable choice for laboratories requiring reproducible reversed-phase HPLC separations.
High-purity silica with octyl (C8) bonded chemistry
Optimized surface for basic and polar analytes
Medium hydrophobic retention with faster elution than C18
Reduced silanol interactions for improved peak symmetry
Available particle sizes: 1.9 µm - 10 µm
Pharmaceutical analysis of basic drugs, alkaloids, and amines
Biochemical separations of polar metabolites and small biomolecules
Food and beverage testing of nitrogen-containing and moderately hydrophobic compounds
Environmental monitoring of cationic and polar organic pollutants
Method development requiring complementary selectivity to C18 phases
| Particle Sizes |
|
|---|---|
| Pore Size | 100 Å |
| Surface Area | 450 m²/g |
| Phase/Modification | C8 |
| Particle Type | |
| Separation Mode | |
| USP Code | |
| Endcapping | Yes |
| Carbonload | 15 % |
| pH Range | 2 to 8 |
| Phase | Material Number |
|---|---|
| ReproSil-Pur Basic-C8, 1.9 µm | r119.b8. |
| ReproSil-Pur Basic-C8, 3 µm | r13.b8. |
| ReproSil-Pur Basic-C8, 5 µm | r15.b8. |
| ReproSil-Pur Basic-C8, 10 µm | r10.b8. |