ReproSil 200 SEC is a silica-based HPLC column with a polyethylene glycol-modified surface, specially designed for size exclusion chromatography (SEC) in the molecular weight range of 10,000 – 500,000 Da. The polyethylene glycol modification minimizes secondary interactions, ensuring accurate size-based separations of large biomolecules and synthetic polymers. The optimized pore structure provides excellent resolution for proteins, nucleic acids, and high-molecular-weight compounds, while the PEG surface coating enhances chemical stability and reproducibility. This makes ReproSil 200 SEC ideally suited for both analytical and preparative SEC applications.
ReproSil 200 SEC combines PEG-modified silica with optimized pore architecture – the reliable choice for high-precision SEC separations in the 10,000–500,000 Da range.
PEG-modified silica phase for size exclusion chromatography
Molecular weight separation range: 10,000 – 500,000 Da
Suppressed secondary interactions for improved accuracy
High stability and reproducibility under routine use
Suitable for analytical and preparative workflows
Manufactured and QC-tested by Dr. Maisch HPLC GmbH
Available in 1.9 µm, 5 µm, and 10 µm particle sizes
Separation and characterization of proteins, enzymes, and nucleic acids
Analysis of biopolymers and synthetic polymers
Molecular weight distribution studies in pharmaceuticals and biotechnology
Fractionation of large biomolecules in biochemical research
| Particle Sizes |
|
|---|---|
| Pore Size | 200 Å |
| Surface Area | 200 m²/g |
| Phase/Modification | PEG |
| Particle Type | |
| Separation Mode | |
| USP Codes | |
| Endcapping | No |
| Carbonload | 15.5 % |
| pH Range | 2 to 8 |
| Phase | Material Number |
|---|---|
| ReproSil 200 SEC, 1.9 µm | r219.sec. |
| ReproSil 200 SEC, 5 µm | r25.sec. |
| ReproSil 200 SEC, 10 µm | r20.sec. |