ReproSil 300 SEC is a silica-based HPLC column specifically optimized for size exclusion chromatography (SEC) in the molecular weight range of 10,000 – 1,000,000 Da. With its large pore structure, the column enables efficient fractionation and accurate size-based separation of very large biomolecules and synthetic polymers. The stationary phase provides high mechanical stability, reproducible retention, and sharp peak shapes, even for complex mixtures. This makes ReproSil 300 SEC an excellent choice for analytical and preparative SEC applications in biochemistry, biotechnology, and polymer research.
ReproSil 300 SEC combines optimized pore design with robust silica performance – the reliable choice for accurate SEC separations in the 10,000–1,000,000 Da range.
Silica-based stationary phase for size exclusion chromatography
Molecular weight separation range: 10,000 – 1,000,000 Da
Optimized pore structure for very large biomolecules and polymers
High reproducibility and robust performance
Suitable for analytical and preparative workflows
Manufactured and QC-tested by Dr. Maisch HPLC GmbH
Available in 3 µm and 5 µm
Separation and analysis of proteins, enzymes, and nucleic acids
Characterization of biopolymers and synthetic polymers up to 1,000 kDa
Molecular weight distribution studies in biotechnology and pharmaceuticals
Fractionation of large biomolecules in biochemical and polymer research
| Particle Sizes |
|
|---|---|
| Pore Size | 300 Å |
| Phase/Modification | Diol |
| Particle Type | |
| Separation Mode | |
| USP Code | |
| Endcapping | No |
| pH Range | 2 to 8 |
| Phase | Material Number |
|---|---|
| ReproSil 300 SEC, 3 µm | r33sec. |
| ReproSil 300 SEC, 5 µm | r35.sec. |