ReproSil Amid-C18 from Dr. Maisch HPLC GmbH is a fully porous, high-purity silica HPLC column with a polar-embedded amid-C18 bonded phase. This stationary phase combines strong hydrophobic retention from the C18 chain with polar interactions from the embedded amide group, delivering improved separation of polar analytes, ionizable compounds, and aromatic systems. The polar-embedded bonding prevents phase collapse in 100% aqueous mobile phases, ensuring stable retention and excellent peak symmetry even for highly hydrophilic compounds.
ReproSil Amid-C18 columns from Dr. Maisch HPLC GmbH provide aqueous stability with enhanced polar selectivity – the perfect choice for challenging reversed-phase HPLC separations.
Fully porous, ultra-pure silica with polar-embedded amid-C18 bonding
Balanced hydrophobic and polar selectivity – USP L1 classification
Stable in 100% aqueous eluents without phase collapse
Enhanced performance for polar, basic, and aromatic analytes
Manufactured and QC-tested by Dr. Maisch HPLC GmbH
Available in 3 µm, 5 µm, amd 10 µm particle sizes
Separation of polar pharmaceuticals and metabolites
100% aqueous reversed-phase HPLC methods
Analysis of hydrophilic natural products and bioactive compounds
Method development requiring mixed-mode selectivity
| Particle Sizes |
|
|---|---|
| Pore Size | 100 Å |
| Surface Area | 280 m²/g |
| Phase/Modification | C18 |
| Particle Type | |
| Separation Modes | |
| USP Codes | |
| Endcapping | No |
| pH Range | 2 to 8 |
| Phase | Material Number |
|---|---|
| ReproSil Amid-C18, 3 µm | r13.a18. |
| ReproSil Amid-C18, 5 µm | r15.a18. |
| ReproSil Amid-C18, 10 µm | r10.a18. |