ReproSil 300 C8 from Dr. Maisch HPLC GmbH is a fully porous, high-purity silica HPLC column with a 300 Å pore size and an octyl bonded phase. Offering moderate hydrophobic retention, this phase is ideal for proteins, peptides, and other large biomolecules, providing faster elution than C18 phases while maintaining excellent resolution. The wide-pore design ensures efficient mass transfer for high-molecular-weight analytes, while the C8 bonding delivers sharp peak shapes, high reproducibility, and robust performance under both isocratic and gradient conditions.
ReproSil 300 C8 columns from Dr. Maisch HPLC GmbH combine balanced retention with wide-pore accessibility – the versatile choice for large biomolecule chromatography in HPLC.
Fully porous, ultra-pure silica with 300 Å pore size
C8 bonding – USP L7 classification
Balanced retention for proteins, peptides, and biomolecules
Faster analysis times compared to C18 wide-pore phases
Manufactured and QC-tested by Dr. Maisch HPLC GmbH
Available in 5 µm and 10 µm particle sizes
Protein and peptide separations in proteomics and biopharma
Large biomolecule analysis in QC and R&D
Gradient separations of amphiphilic biomolecules
Method development requiring moderate hydrophobicity
| Particle Sizes |
|
|---|---|
| Pore Size | 300 Å |
| Surface Area | 100 m²/g |
| Phase/Modification | C8 |
| Particle Type | |
| Separation Mode | |
| USP Code | |
| Endcapping | Yes |
| pH Range | 2 to 8 |
| Phase | Material Number |
|---|---|
| ReproSil 300 C8, 5 µm | r35.86. |
| ReproSil 300 C8, 10 µm | r30.86. |