Reprospher 100 Biphenyl

π-Enhanced Reversed-Phase Column for Aromatic and Structural Isomer Separations

Reprospher 100 Biphenyl is a reversed-phase HPLC column from Dr. Maisch HPLC GmbH, featuring a biphenyl-bonded stationary phase on high-purity, fully porous silica with a 100 Å pore size. The biphenyl ligand introduces strong π-π interaction capabilities, enabling selective retention and resolution of aromatic compounds, ring systems, and structurally related isomers. In contrast to classical C18 columns, Reprospher 100 Biphenyl offers orthogonal selectivity, improved separation of planar and conjugated analytes, and enhanced differentiation of closely eluting compounds. It is especially valuable in pharmaceutical, environmental, and food analysis where aromatic compound separation is critical.

Reprospher 100 Biphenyl from Dr. Maisch HPLC GmbH delivers advanced reversed-phase performance with distinct aromatic selectivity – ideal for challenging HPLC separations of structurally related and aromatic analytes.

Key Features:

  • Biphenyl bonded reversed-phase phase – USP L11 equivalent

  • Strong π-π selectivity for aromatic and planar compounds

  • Fully porous silica with 100 Å pore size

  • Enhanced retention of phenolic compounds, aromatics, and isomers

  • Stable and reproducible performance across a broad pH range

Typical Applications:

  • Aromatic compound separations in pharmaceuticals and natural products

  • Isomer resolution and fingerprinting in complex mixtures

  • Orthogonal method development in reversed-phase HPLC

  • Environmental and food sample analysis involving phenols or benzene derivatives

Specifications

Request Product
Particle Sizes
  • 3 µm
  • 5 µm
Pore Size 100 Å
Surface Area 350 m²/g
Phase/Modification Biphenyl
Particle Type
Separation Mode
USP Code
Endcapping Yes
Carbonload 14 %
pH Range 2 to 8

Material Numbers

Phase Material Number
Reprospher 100 Biphenyl, 3 µm rs13.bpe
Reprospher 100 Biphenyl, 5 µm rs15.bpe.
Reprospher 100 4-EP Reprospher 100 C4

Any questions?
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info@dr-maisch.com +49 7073 5035 7

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