Reprospher 100 Phenyl-NE is a reversed-phase HPLC column from Dr. Maisch HPLC GmbH, based on high-purity, fully porous silica with a 100 Å pore size and bonded with phenyl ligands. The phase is non-endcapped, which preserves residual silanol groups on the silica surface. This creates additional polar interaction sites that complement the π–π selectivity of the phenyl group, resulting in an extended range of separation mechanisms. This unique selectivity profile is especially beneficial for the separation of aromatic, polar, and ionizable compounds and provides an orthogonal alternative to standard endcapped reversed-phase columns.
Reprospher 100 Phenyl-NE from Dr. Maisch HPLC GmbH offers combined π–π and polar selectivity – ideal for challenging reversed-phase separations where fine-tuned interaction mechanisms are required.
Phenyl bonded phase – USP L11 classification
Non-endcapped for enhanced polar and π–π interactions
Fully porous, high-purity silica with 100 Å pore size
Ideal for structurally similar, polar, and aromatic compounds
Available in 5 µm
Separation of positional isomers, phenolic compounds, and bioactive aromatics
Retention tuning of polar or weakly retained analytes
Orthogonal method development in pharmaceutical and environmental analysis
HPLC workflows requiring alternative selectivity to C18 or endcapped phenyl phases
| Particle Size |
|
|---|---|
| Pore Size | 100 Å |
| Surface Area | 350 m²/g |
| Phase/Modification | Phenyl |
| Particle Type | |
| Separation Mode | |
| USP Code | |
| Endcapping | No |
| Carbonload | 12 % |
| pH Range | 2 to 8 |
| Phase | Material Number |
|---|---|
| Reprospher 100 Phenyl-NE, 5 µm | rs15.p0. |