Reprospher 100 Si is a high-purity, unmodified silica HPLC column from Dr. Maisch HPLC GmbH, packed with fully porous silica featuring a 100 Å pore size. The bare silica surface provides strong polar interactions via exposed silanol groups, making this column ideal for classical normal-phase chromatography and adsorption-based separations. It offers high separation efficiency and reproducible retention for polar, neutral, and isomeric compounds — especially when using non-polar eluents. This phase is widely applied in method development, compound screening, and preparative normal-phase chromatography.
Reprospher 100 Si from Dr. Maisch HPLC GmbH offers classical silica performance with consistent retention – the reliable choice for normal-phase chromatography and polarity-driven separations.
Unmodified (bare) silica phase – USP L3 classification
Fully porous, high-purity silica with 100 Å pore size
Strong polar interaction via active silanol groups
Ideal for normal-phase and dry-loading workflows
Available in from 1.7 µm to 10 µm particle sizes
Normal-phase separations of polar organic compounds and isomers
Adsorption chromatography and fractionation of non-polar matrices
Sample pre-purification and flash/prep column screening
Orthogonal selectivity to reversed-phase HPLC
| Particle Sizes |
|
|---|---|
| Pore Size | 100 Å |
| Surface Area | 350 m²/g |
| Phase/Modification | Si |
| Particle Type | |
| Separation Modes | |
| USP Code | |
| Endcapping | No |
| Carbonload | 0 % |
| pH Range | 2 to 8 |
| Phase | Material Number |
|---|---|
| Reprospher 100 Si, 1.7 µm | rs117.00. |
| Reprospher 100 Si, 1.8 µm | rs118.00. |
| Reprospher 100 Si, 2 µm | rs12.00. |
| Reprospher 100 Si, 2.5 µm | rs125.00. |
| Reprospher 100 Si, 3 µm | rs13.00. |
| Reprospher 100 Si, 5 µm | rs15.00. |
| Reprospher 100 Si, 7 µm | rs17.00. |
| Reprospher 100 Si, 10 µm | rs10.00. |