Reprospher 200 C18-DE

Double Endcapped C18 Reversed-Phase Column for Superior Peak Symmetry

Reprospher 200 C18-DE is a high-performance reversed-phase HPLC column from Dr. Maisch HPLC GmbH, packed with ultra-pure, fully porous spherical silica (200 Å pore size) bonded with octadecyl ligands and double endcapped to maximize deactivation of residual silanol groups. This advanced surface treatment ensures excellent peak symmetry, particularly for basic and polar analytes, and provides high reproducibility even under demanding conditions. The wide pore size makes this phase especially suitable for the analysis of larger biomolecules such as peptides, oligonucleotides, and other macromolecules, while the double endcapping enhances robustness and column lifetime.

Reprospher 200 C18-DE from Dr. Maisch HPLC GmbH delivers premium reversed-phase performance – the ideal choice for laboratories requiring excellent peak symmetry, high stability, and reliable separation of larger analytes.

Key Features:

  • Trifunctional C18 bonding with double endcapping – USP L1

  • 200 Å pore size for peptides and larger biomolecules

  • Excellent peak symmetry for basic and polar analytes

  • High mechanical and chemical stability for demanding applications

  • Manufactured and QC-tested by Dr. Maisch HPLC GmbH

  • Available in 1.8 µm, 2 µm, 2.5 µm and 3 µm particle sizes

Typical Applications:

  • Reversed-phase HPLC of peptides, oligonucleotides, and biomolecules

  • Pharmaceutical impurity profiling and stability-indicating assays

  • Gradient and isocratic separations with high reproducibility

  • Method development requiring robust peak shape improvement

Specifications

Request Product
Particle Sizes
  • 1.8 µm
  • 2 µm
  • 2.5 µm
  • 3 µm
Pore Size 200 Å
Surface Area 160 m²/g
Phase/Modification C18
Particle Type
Separation Mode
USP Code
Endcapping Yes
Carbonload 10 %
pH Range 2 to 8

Material Numbers

Phase Material Number
Reprospher 200 C18-DE, 1.8 µm rs218.9de.
Reprospher 200 C18-DE, 2 µm rs22.9de.
Reprospher 200 C18-DE, 2.5 µm rs225.9de.
Reprospher 200 C18-DE, 3 µm rs23.9de.
Reprospher 200 C18-Aqua Reprospher 200 C18-TDE

Any questions?
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info@dr-maisch.com +49 7073 5035 7

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