Reprospher 200 C18-TDE

Trifunctional C18 Reversed-Phase Column with High Endcapping for Biomolecule Analysis

Reprospher 200 C18-TDE is a high-performance reversed-phase HPLC column from Dr. Maisch HPLC GmbH, packed with ultra-pure, fully porous spherical silica (200 Å pore size) functionalized with trifunctionally bonded octadecyl (C18) chains and featuring high-density endcapping (TDE). This design ensures maximum deactivation of residual silanol groups, resulting in excellent peak symmetry and reproducibility, even for basic and polar analytes. The wide pore size of 200 Å makes the column particularly suitable for the analysis of peptides, oligonucleotides, proteins, and other large biomolecules, while the trifunctional bonding provides enhanced phase stability and extended column lifetime.

Reprospher 200 C18-TDE from Dr. Maisch HPLC GmbH delivers premium reversed-phase performance – the ideal choice for laboratories working with biomolecules and complex pharmaceutical analytes where peak symmetry and column stability are critical.

Key Features:

  • Trifunctional C18 bonding with high-density endcapping – USP L1

  • 200 Å pore size optimized for biomacromolecules

  • Excellent peak shape for peptides and basic compounds

  • High mechanical and chemical stability for robust performance

  • Manufactured and QC-tested by Dr. Maisch HPLC GmbH

  • Available in 5 µm

Typical Applications:

  • Reversed-phase HPLC of peptides, proteins, and oligonucleotides

  • Pharmaceutical QC and biopharmaceutical impurity profiling

  • Gradient separations with reproducible retention of large molecules

  • Method development requiring robust stability and superior peak shape

Specifications

Request Product
Particle Size
  • 5 µm
Pore Size 200 Å
Surface Area 160 m²/g
Phase/Modification C18
Particle Type
Separation Mode
USP Code
Endcapping Yes
Carbonload 12 %
pH Range 2 to 8

Material Number

Phase Material Number
Reprospher 200 C18-TDE, 5 µm rs25.9tde.
Reprospher 200 C18-DE Reprospher 200 C18-TN

Any questions?
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info@dr-maisch.com +49 7073 5035 7

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