Reprospher 300 C18-DE is a high-performance reversed-phase HPLC column from Dr. Maisch HPLC GmbH, packed with ultra-pure, fully porous spherical silica (300 Å pore size) bonded with octadecyl ligands and double endcapped for maximum deactivation of residual silanol groups. This advanced surface treatment ensures excellent peak symmetry and reproducibility, particularly for basic and polar analytes, while maintaining strong hydrophobic retention. The wide 300 Å pore structure is optimized for the analysis of peptides, proteins, and other large biomolecules, allowing efficient mass transfer and reliable recovery of high-molecular-weight compounds. The double endcapping provides superior stability and column lifetime in demanding reversed-phase applications.
Reprospher 300 C18-DE from Dr. Maisch HPLC GmbH delivers robust and reliable performance – the ideal choice for laboratories analyzing large biomolecules and complex pharmaceutical samples where peak symmetry and stability are essential.
C18 reversed-phase silica with double endcapping – USP L1
300 Å pore size ideal for peptides, proteins, and biomolecules
Excellent peak shape for basic and polar analytes
Strong hydrophobic retention with high reproducibility
Manufactured and QC-tested by Dr. Maisch HPLC GmbH
Available in 2.5 µm, 3 µm and 5 µm particle sizes
Reversed-phase HPLC of peptides, proteins, and oligonucleotides
Bioanalytical workflows for therapeutic biomolecules
Gradient separations with reproducible retention of large analytes
Pharmaceutical QC and stability-indicating methods
| Particle Sizes |
|
|---|---|
| Pore Size | 300 Å |
| Surface Area | 100 m²/g |
| Phase/Modification | C18 |
| Particle Type | |
| Separation Mode | |
| USP Code | |
| Endcapping | Yes |
| Carbonload | 7 % |
| pH Range | 2 to 8 |
| Phase | Material Number |
|---|---|
| Reprospher 300 C18-DE, 2.5 µm | rs325.9de. |
| Reprospher 300 C18-DE, 3 µm | rs33.9de. |
| Reprospher 300 C18-DE, 5 µm | rs35.9de. |