Reprospher 300 C18-T

Trifunctional C18 Reversed-Phase Column for Robust Biomolecule Analysis

Reprospher 300 C18-T is a high-performance reversed-phase HPLC column from Dr. Maisch HPLC GmbH, packed with ultra-pure, fully porous spherical silica (300 Å pore size) functionalized with trifunctionally bonded octadecyl ligands. This bonding technology ensures superior phase stability and durability, providing strong hydrophobic retention with excellent reproducibility, even under demanding gradient conditions. The wide 300 Å pore size is specifically designed for large biomolecules such as proteins, peptides, and oligonucleotides, ensuring efficient mass transfer and high recovery. The trifunctional bonding further enhances column lifetime and robustness, making it suitable for both routine bioanalytical workflows and advanced method development.

Reprospher 300 C18-T from Dr. Maisch HPLC GmbH delivers robust performance and strong hydrophobic selectivity – the ideal column for laboratories analyzing complex biomolecules with high reliability and reproducibility.

Key Features:

  • Trifunctional C18 bonding on ultra-pure spherical silica – USP L1

  • 300 Å pore size optimized for proteins, peptides, and biomolecules

  • Strong hydrophobic retention with robust reproducibility

  • High stability for gradient and high-demand HPLC applications

  • Manufactured and QC-tested by Dr. Maisch HPLC GmbH

  • Available in 5 µm

Typical Applications:

  • Reversed-phase HPLC of peptides, proteins, and oligonucleotides

  • Pharmaceutical and biopharmaceutical analysis of biomacromolecules

  • Gradient separations of large, hydrophobic analytes

  • Method development requiring maximum phase stability

Specifications

Request Product
Particle Size
  • 5 µm
Pore Size 300 Å
Surface Area 100 m²/g
Phase/Modification C18
Particle Type
Separation Mode
USP Code
Endcapping Yes
Carbonload 11 %
pH Range 2 to 8

Material Number

Phase Material Number
Reprospher 300 C18-T, 5 µm rs35.9t.
Reprospher 300 C18-DE Reprospher 300 C18-TN

Any questions?
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info@dr-maisch.com +49 7073 5035 7

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