Reprospher 300 C8-T is a high-performance reversed-phase HPLC column from Dr. Maisch HPLC GmbH, packed with ultra-pure, fully porous spherical silica (300 Å pore size) functionalized with trifunctionally bonded octyl ligands. The medium-chain C8 bonding provides moderate hydrophobic retention, making it ideal for analytes that are over-retained on C18 but still require stronger interaction than C4. The wide pore size (300 Å) ensures efficient access and mass transfer for peptides, proteins, and other large biomolecules, while the trifunctional bonding chemistry delivers enhanced stability, reproducibility, and extended column lifetime under demanding analytical conditions.
Reprospher 300 C8-T from Dr. Maisch HPLC GmbH offers robust reversed-phase performance with balanced hydrophobicity – the ideal choice for laboratories working with biomolecules and peptides in pharmaceutical and biotechnological analysis.
Trifunctional C8 bonding on spherical silica – USP L7
300 Å pore size optimized for peptides, proteins, and biomolecules
Moderate hydrophobic retention for balanced selectivity
High chemical and mechanical stability for reproducible performance
Manufactured and QC-tested by Dr. Maisch HPLC GmbH
Available in 5 µm
Reversed-phase HPLC of peptides, proteins, and oligonucleotides
Bioanalytical separations requiring moderate retention strength
Gradient methods for biomolecule profiling and impurity analysis
Method development where C18 is too retentive and C4 too weak
| Particle Size |
|
|---|---|
| Pore Size | 300 Å |
| Surface Area | 100 m²/g |
| Phase/Modification | C8 |
| Particle Type | |
| Separation Mode | |
| USP Code | |
| Endcapping | Yes |
| Carbonload | 6 % |
| pH Range | 2 to 8 |
| Phase | Material Number |
|---|---|
| Reprospher 300 C8-T, 5 µm | rs35.8t. |